000			04998cam a2200613 i 4500
001			ocn839677985
003			OCoLC
005			20221128212241.0
006			m d
007			cr |||||||||||
008			120809s2012 nyu o 001 0 eng
010			_a 2020676506
040			_aDLC _beng _erda _cDLC _dYDXCP _dE7B _dEBLCP _dOCLCF _dAU@ _dSTF _dN$T
020			_a9781619427549 _q(ebook)
020			_a1619427540
020			_z9781619427419 _q(hardcover)
020			_z1619427419 _q(hardcover)
035			_a564942 _b(N$T)
035			_a(OCoLC)839677985
042			_apcc
072		7	_aMED _x010000 _2bisacsh
049			_aMAIN
245	0	0	_aGene therapy for cardiovascular diseases and arrhythmia _c _h[E-Book]
264		1	_aNew York : _bNova Biomedical, _c[2012]
300			_a1 online resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
490	1		_aCardiology research and clinical developments
500			_aIncludes index.
588			_aDescription based on print version record.
505	0		_aGENE THERAPY FOR CARDIOVASCULAR DISEASES AND ARRHYTHMIA; GENE THERAPY FOR CARDIOVASCULAR DISEASES AND ARRHYTHMIA; Library of Congress Cataloging-in-Publication Data; Contents; Preface; Introduction; Chapter I: General Principles of Gene Transfer; 1.1. Viral and Non-viral Gene Delivery; 1.2. Adenovirus; 1.3. Adeno-Associated Virus (AAV); 1.4. Retroviruses; 1.5. Lentivirus; 1.6. Naked DNA; References; Chapter II: Gene Delivery Techniques; 2.1. Current Cardiac Gene Delivery Techniques; 2.2. Direct Gene Delivery; 2.3. Intracoronary Infusion; References.
505	8		_aChapter III: Gene Therapy for Coronary Artery and IschemicHeart Disease3.1. Coronary Artery and Ischemic Heart Disease; 3.2. Gene Therapy for Coronary Atherosclerosis; 3.3. Gene Therapy for Angiogenesis in Ischemia; 3.4. Gene Therapy for Myocardial Reperfusion Injury; References; Chapter IV: Gene Therapy for Heart Failure; References; Chapter V: Viral Gene Therapy in Myocarditis; 5.1. Myocarditis, at the Bedside; 5.2. Myocarditis, at the Bench; 5.2.1. Experimental Animal Models and Pathophysiology; 5.2.2. Experimental Viral Myocarditis; 5.2.3. Experimental Autoimmune Myocarditis.
505	8		_a5.2.4. Virus-Associated Gene Transfer5.3. Study Limitations and Open Questions; References; Chapter VI: Gene Therapy for Atrial Arrhythmia: A Therapeutic Approach for Atrial Fibrillation; References; Chapter VII: Gene Therapy for Ventricular Arrhythmia; References; Chapter VIII: Stem Cell Therapy for Cardiovascular Disease; 8.1. Promises and Limitations of Different Cell Populations; 8.1.1. General Aspects; 8.1.2. Differentiation Potential; 8.1.3. Cell Sources in Detail (for Summary Refer to Table 1); 8.1.3.1. Bone Marrow Mononuclear Cells; 8.1.3.2. Mesenchymal Stem Cells.
505	8		_a8.1.3.3. CD133+ Progenitor Cells8.1.3.4. CD34+ Progenitor Cells; 8.1.3.5. Myoblasts; 8.1.3.6. Resident Myocardial Progenitor Cells; 8.1.3.7. Embryonic Stem Cells; 8.1.3.8. Induced Pluripotent Stem Cells; 8.2. Stem Cell Delivery; 8.2.1. Intravenous Administration; 8.2.2. Myocardial Injection; 8.2.3. Intracoronary Delivery; 8.3. Cytokine Therapy; 8.4. Mechanisms of Cell-Based Therapy; 8.4.1. Stem Cell Homing; 8.4.2. Stem Cell Migration within the Myocardium; 8.4.3. Precommitment Versus in Vivo Differentiation; 8.4.4. Transdifferentiation versus Cell Fusion.
505	8		_a8.4.5. Paracrine Effects of Stem Cell Therapy8.5. Stem Cell versus Gene Therapy; 8.6. Future Directions of Cardiovascular Cell-Therapy; 8.6.1. Priming of Stem Cells; 8.6.2. Bionanotechnology to Restore Extracellular Matrix; 8.6.3. Tissue Engineering; References; Chapter IX: Gene Transfer for the Development of a Biological Pacemaker; 9.1. Anatomy and Physiology of the Human Pacemaker; 9.1.1. Anatomic Basis of the Pacemaker; 9.1.2. Differences in the Action Potential between Pacemaker and Non-Pacemaker Cells; 9.1.2.1. Ventricular Myocyte (Non-Pacemaker Cell) Action Potentials.
590			_aMaster record variable field(s) change: 050
650		0	_aCardiovascular system _xDiseases _xTreatment.
650		0	_aArrhythmia _xTreatment.
650		0	_aCardiovascular system _xDiseases _xGene therapy.
650		0	_aArrhythmia _xGene therapy.
650		0	_aGene therapy.
700	1		_aKelemen, Kamilla, _d1976- _eauthor.
700	1		_aSchweizer, P. _q(Patrick) _eauthor.
700	1		_aLi, Jin, _d1985- _eauthor.
830		0	_aCardiology research and clinical developments series.
856	4	0	_uhttps://search.ebscohost.com/login.aspx?custid=ns123844&authtype=ip,shib&direct=true&scope=site&db=nlebk&db=nlabk&AN=564942 _yKingston Hospital NHS Foundation Trust OpenAthens account holders click here for access
938			_aYBP Library Services _bYANK _n7422944
938			_aEBSCOhost _bEBSC _n564942
938			_aebrary _bEBRY _nebr10687818
938			_aProQuest Ebook Central _bEBLB _nEBL3022161
942			_n0
994			_a92 _bN$T
999			_c91162 _d91162