Fetal medicine: basic science and clinical practice

Early concepts and terminology -- Cellular mechanisms and embryonic tissues -- Staging embryos in development and the embryonic body plan -- Teratology -- Early pregnancy failure -- The immunology of implantation -- Development of the placenta and its circulation -- Placental function in maternofetal exchange -- Placental pathology and implications for fetal medicine -- Development of the heart and cardiovascular system in relation to cardiac abnormalities -- Lung growth and maturation -- Development of the kidneys and urinary tract in relation to renal anomalies -- The perinatal postmortem examination -- Epidemiologic and research methods in fetal medicine -- Ethical issues in maternal-fetal medicine -- Principles of screening -- Conveying information about screening and diagnosis -- Ultrasound and biochemical screening for fetal aneuploidy -- Ultrasound screening for fetal abnormalities in the first trimester -- Evidence for routine ultrasound screening for fetal abnormalities in the second and third trimesters -- Noninvasive screening for cytogenetic disorders (fetal aneuploidy including microdeletions) -- Noninvasive prenatal diagnosis for single-gene disorders -- Invasive diagnostic procedures -- Prenatal diagnosis of chromosome abnormalities -- Advances in molecular genetics including fetal sequencing -- Expanded carrier screening -- Prenatal screening for thalassemias -- Sonography of the fetal central nervous system -- The heart -- Fetal lung lesions -- Congenital diaphragmatic hernia -- Abdomen -- Kidney and urinary tract disorders -- Diagnosis and management of fetal skeletal abnormalities -- Diagnosis and management of abnormalities of the face -- Fetal hydrops -- Fetal tumours -- Open fetal surgery -- Fetal growth and growth restriction -- Haemolytic disease of the fetus and newborn -- Fetal platelet disorders -- Fetal infections -- Disorders of amniotic fluid -- Multiple pregnancy -- In utero stem cell transplantation -- Fetal gene therapy -- The developmental origins of health and disease -- Pharmacokinetics and pharmacodynamics -- Neonatal management and outcome in extreme prematurity -- Self-assessment.

Covering pertinent basic science and offering today's most authoritative guidance on clinical management, Fetal Medicine, 3rd Edition, is a must-have resource for obstetricians and other healthcare professionals involved in care of the fetus. An international team of expert contributors delivers the knowledge and background you need to effectively diagnose and treat fetal disorders - everything from prenatal screening and diagnostic tests to common and rare prenatal conditions, early pregnancy loss, ethical issues, and much more. Focuses on fetal medicine throughout, bringing you today's most reliable information in both basic science and clinical topics. Offers updated information from cover to cover, including new coverage of genetics, embryology, and clinical management. Features new self-assessment questions, new video clips, and new images throughout - for a total of nearly 1,000 photographs and line drawings, as well as more than 150 quick-reference tables. Details fast-changing developments in fetal medicine, including advances in ultrasound imaging, cytogenetics, molecular biology, and biochemistry. Helps you learn and retrieve complex information quickly thanks to succinct, highly structured text; key points at the beginning of each chapter; and concise chapter summaries. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.