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Fertility preservation in male cancer patients [electronic resource] /

Contributor(s): Publication details: Cambridge : Cambridge University Press, 2013.Description: 1 online resourceISBN:
  • 9781139625104 (electronic bk.)
  • 1139625101 (electronic bk.)
Subject(s): Online resources:
Contents:
Contributors; Section 1 -- Anatomy and physiology; 1 Functional anatomy of the hypothalamic-pituitary-gonadal axis and the male reproductive tract; Anatomy of reproductive function; Hypothalamus and anterior pituitary gland; Gonadotropin-releasing hormone (GnRH); Gonadotropic hormones: LH and FSH; Testosterone and LH; Negative feedback of testosterone; Testosterone and FSH; Inhibin; Testis; Arterial and venous supply; Testicular organization; Spermatogenesis; Epididymis; Innervation; Arterial and venous supply; Epididymal function; Storage of sperm; Maturation of sperm.
Transport of spermVas deferens and ejaculatory duct; Seminal vesicles; Prostate; Bulbourethral glands; Penis; Arterial and venous supply; Neuroanatomy; Erection and detumescence: cavernosal smooth muscle physiology; References; 2 Spermatogenesis; Introduction; Macroscopic testicular anatomy; The epididymis; The vas deferens; Microscopic anatomy; The Leydig cell; The Sertoli cell; The blood-testis barrier; Spermatogenesis; Meiosis; Regulation of spermatogensis: the hypothalamic-pituitary-gonadal (HPG) axis; Conclusion; Acknowledgments; References; 3 The semen analysis; Introduction.
Technical considerationsMacroscopic characteristics; Gross appearance; Semen volume; pH; Liquefaction; Microscopic characteristics; Viscosity; Count and concentration; Motility; Computer-assisted sperm assessment (CASA); Morphology; Viability; Anti-sperm antibodies (ASA); Other cell types; Biochemical analysis; Semen analysis in cancer patients; Predictive parameters for successful fertility; Conclusion; Acknowledgments; References; 4 Physiology of ejaculation; Emission and ejaculation; Neuroanatomy; Peripheral anatomy; Spinal and central anatomy; Physiological control of ejaculation; Summary.
Tests of sperm functionTests of sperm DNA integrity; Impact of cancer and cancer therapies on semen parameters; Summary; References; 7 Azoospermia; Introduction; Classification of azoospermia into diagnostic categories; Initial evaluation of the azoospermic male; Indications for treatment of men with azoospermia; Treatment of non-obstructive azoospermia; Treatment of obstructive azoospermia; Conclusion; References; 8 Varicocele; Introduction; Pathophysiology of varicocele; Clinical features of varicocele; Evaluation of men with suspected varicoceles; Indications for varicocele treatment.
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Special considerations in men with cancer.

Written by international authorities, this book is aimed at clinicians dealing with male patients rendered infertile by cancer therapy.

ReferencesSection 2-Disorders of male fertility; 5 History and physical examination; Introduction; History; Reproductive history; Childhood illnesses and conditions; Systemic diseases; Past surgical history; Family history; Medications; Lifestyle exposures and occupational history; Cancer and cancer therapies; Testicular cancer; Hodgkins disease (HD); Cancer therapies; Physical examination; Penis; Scrotum; Digital rectal examination; Summary; References; 6 Abnormalities of semen parameters; Introduction; Low-volume ejaculate; Oligospermia; Asthenospermia; Teratospermia; Leukocytospermia.

Contributors; Section 1 -- Anatomy and physiology; 1 Functional anatomy of the hypothalamic-pituitary-gonadal axis and the male reproductive tract; Anatomy of reproductive function; Hypothalamus and anterior pituitary gland; Gonadotropin-releasing hormone (GnRH); Gonadotropic hormones: LH and FSH; Testosterone and LH; Negative feedback of testosterone; Testosterone and FSH; Inhibin; Testis; Arterial and venous supply; Testicular organization; Spermatogenesis; Epididymis; Innervation; Arterial and venous supply; Epididymal function; Storage of sperm; Maturation of sperm.

Transport of spermVas deferens and ejaculatory duct; Seminal vesicles; Prostate; Bulbourethral glands; Penis; Arterial and venous supply; Neuroanatomy; Erection and detumescence: cavernosal smooth muscle physiology; References; 2 Spermatogenesis; Introduction; Macroscopic testicular anatomy; The epididymis; The vas deferens; Microscopic anatomy; The Leydig cell; The Sertoli cell; The blood-testis barrier; Spermatogenesis; Meiosis; Regulation of spermatogensis: the hypothalamic-pituitary-gonadal (HPG) axis; Conclusion; Acknowledgments; References; 3 The semen analysis; Introduction.

Technical considerationsMacroscopic characteristics; Gross appearance; Semen volume; pH; Liquefaction; Microscopic characteristics; Viscosity; Count and concentration; Motility; Computer-assisted sperm assessment (CASA); Morphology; Viability; Anti-sperm antibodies (ASA); Other cell types; Biochemical analysis; Semen analysis in cancer patients; Predictive parameters for successful fertility; Conclusion; Acknowledgments; References; 4 Physiology of ejaculation; Emission and ejaculation; Neuroanatomy; Peripheral anatomy; Spinal and central anatomy; Physiological control of ejaculation; Summary.

Tests of sperm functionTests of sperm DNA integrity; Impact of cancer and cancer therapies on semen parameters; Summary; References; 7 Azoospermia; Introduction; Classification of azoospermia into diagnostic categories; Initial evaluation of the azoospermic male; Indications for treatment of men with azoospermia; Treatment of non-obstructive azoospermia; Treatment of obstructive azoospermia; Conclusion; References; 8 Varicocele; Introduction; Pathophysiology of varicocele; Clinical features of varicocele; Evaluation of men with suspected varicoceles; Indications for varicocele treatment.

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