Best Practices of Apheresis in Hematopoietic Cell Transplantation

Introduction and rationale; Administrative and regulatory considerations for apheresis collection facilities; FACT-JACIE standards - common citations and how best to avoid them; Donor evaluation for hematopoietic stem and progenitor cell collection; Mobilization strategies - HPC(A) collections for autologous hematopoietic cell transplants; Mobilization strategies - HPC(A) collections for allogeneic hematopoietic cell transplants; Hematopoietic progenitor cells, apheresis and therapeutic cells, t-cells collection - instrumentation, operating parameters and troubleshooting; Anticoagulation and other periprocedural considerations for apheresis; Concepts and rationale for using perdictive algorithms for hematopoietic progenitor cell apheresis collection; Applications of apheresis devices in processing bone marrow grafts; Therapeutic plasma exchange and immunoadsorption - indications and implementation; Red blood cell exchange - when and why?; Extracorporeal photopheresis in hematopoietic cell transplantation; Prevention and management of apheresis complications; Challanges and optimization of apheresis procedures in resource-limiting environments

n this book, world-renowned experts in the field of hematopoietic cell transplantation examine a range of issues and controversies relating to apheresis, with the aim of identifying current trends and best practices