MARC details
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07821cam a2200853Ma 4500 |
| 001 - CONTROL NUMBER |
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ocn608623797 |
| 003 - CONTROL NUMBER IDENTIFIER |
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OCoLC |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20221128211130.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS--GENERAL INFORMATION |
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m d |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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cr cn||||||||| |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
070223s2008 njua ob 001 0 eng d |
| 010 ## - LIBRARY OF CONGRESS CONTROL NUMBER |
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| Canceled/invalid LC control number |
2007008049 |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
MERUC |
| 015 ## - NATIONAL BIBLIOGRAPHY NUMBER |
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| National bibliography number |
GBA768712. |
| Source |
bnb |
| 015 ## - NATIONAL BIBLIOGRAPHY NUMBER |
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| National bibliography number |
GBA768712 |
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bnb |
| 016 7# - NATIONAL BIBLIOGRAPHIC AGENCY CONTROL NUMBER |
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| Record control number |
1063030358 |
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DE-101 |
| 016 7# - NATIONAL BIBLIOGRAPHIC AGENCY CONTROL NUMBER |
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| Canceled or invalid record control number |
101300031 |
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DNLM |
| 016 7# - NATIONAL BIBLIOGRAPHIC AGENCY CONTROL NUMBER |
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| Canceled or invalid record control number |
013828938 |
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Uk |
| 019 ## - |
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214281464 |
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228431849 |
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429918459 |
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476150171 |
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492166591 |
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647763039 |
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703214947 |
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722716613 |
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728056541 |
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746500941 |
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746571436 |
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815562144 |
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850628590 |
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961555826 |
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962677397 |
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966211067 |
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988409351 |
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992024411 |
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992822972 |
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1038606600 |
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1062883874 |
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1081247342 |
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1153468164 |
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1162032621 |
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1191084856 |
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1200917542 |
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1228579972 |
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1241943299 |
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1290086087 |
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1300646635 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| ISBN |
9780470184585 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| ISBN |
0470184582 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| ISBN |
9780470184578 |
| Qualifying information |
(electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| ISBN |
0470184574 |
| Qualifying information |
(electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| ISBN |
1281284424 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| ISBN |
9781281284426 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| ISBN |
9786611284428 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| ISBN |
6611284427 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| Cancelled/invalid ISBN |
9780471703204 |
| Qualifying information |
(hbk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| Cancelled/invalid ISBN |
0471703206 |
| Qualifying information |
(hbk.) |
| 035 ## - SYSTEM CONTROL NUMBER |
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| System control number |
225566 |
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(N$T) |
| 035 ## - SYSTEM CONTROL NUMBER |
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| System control number |
(OCoLC)608623797 |
| Canceled/invalid control number |
(OCoLC)214281464 |
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(OCoLC)228431849 |
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(OCoLC)429918459 |
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(OCoLC)476150171 |
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(OCoLC)492166591 |
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(OCoLC)647763039 |
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(OCoLC)703214947 |
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(OCoLC)722716613 |
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(OCoLC)728056541 |
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(OCoLC)746500941 |
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(OCoLC)746571436 |
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(OCoLC)815562144 |
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(OCoLC)850628590 |
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(OCoLC)961555826 |
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(OCoLC)962677397 |
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(OCoLC)966211067 |
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(OCoLC)988409351 |
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(OCoLC)992024411 |
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(OCoLC)992822972 |
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(OCoLC)1037750121 |
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(OCoLC)1038606600 |
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(OCoLC)1045536572 |
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(OCoLC)1062883874 |
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(OCoLC)1081247342 |
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(OCoLC)1153468164 |
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(OCoLC)1162032621 |
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(OCoLC)1191084856 |
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(OCoLC)1200917542 |
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(OCoLC)1228579972 |
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(OCoLC)1241943299 |
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(OCoLC)1290086087 |
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(OCoLC)1300646635 |
| 060 #4 - NATIONAL LIBRARY OF MEDICINE CALL NUMBER |
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| Classification number |
2008 D-158 |
| 060 #4 - NATIONAL LIBRARY OF MEDICINE CALL NUMBER |
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| Classification number |
QZ 52 |
| Item number |
C744 2008 |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
HEA |
| Subject category code subdivision |
039060 |
| Source |
bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
MED |
| Subject category code subdivision |
107000 |
| Source |
bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
K |
| Source |
bicssc |
| 049 ## - LOCAL HOLDINGS (OCLC) |
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| Holding library |
MAIN |
| 245 00 - TITLE STATEMENT |
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| Title |
Concepts in genetic medicine |
| Statement of responsibility, etc |
|
| Medium |
[E-Book] |
| 260 ## - PUBLICATION INFORMATION |
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| Place of publication |
Hoboken, N.J. : |
| Publisher |
Wiley-Liss, |
| Date |
2008. |
| 300 ## - PHYSICAL DESCRIPTION |
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| Physical description |
1 online resource (xiii, 377 pages) : |
| Other physical details |
illustrations |
| 336 ## - CONTENT TYPE |
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| Content type term |
text |
| Content type code |
txt |
| Source |
rdacontent |
| 337 ## - MEDIA TYPE |
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| Media type term |
computer |
| Media type code |
c |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
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| Carrier type term |
online resource |
| Carrier type code |
cr |
| Source |
rdacarrier |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
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| Bibliography, etc |
Includes bibliographical references and index. |
| 505 0# - CONTENTS |
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| Contents |
Cover -- TOC36;CONTENTS -- CONTRIBUTORS -- PREFACE -- INTRODUCTION -- CH36;1 The Evolution of Human Gene Therapy58; A Journey from Excessive Hype to Excessive Diffidence to Reality -- VECTOR SYSTEMS -- CH36;2 Murine Leukemia Virus8211;Based Retroviral Vectors -- CH36;3 Lentivirus Vectors -- CH36;4 Adenoviral Vectors58; History and Perspective -- CH36;5 Adeno45;Associated Virus Vectors -- CH36;6 SV40 Virus8211;Derived Vectors -- CH36;7 Herpes Simplex Virus Vectors -- CH36;8 Nonviral Gene Delivery Systems -- APPLICATIONS -- CH36;9 Therapeutic Gene Transfer to Skeletal Muscle -- CH36;10 Gene Therapy for Cardiovascular Disease -- CH36;11 Intraarticular Vector Delivery for Inflammatory Joint Disease -- CH36;12 The Respiratory System as a Platform for Gene Delivery -- CH36;13 The Brain as a Target for Gene Therapy -- CH36;14 Immune Responses to Viral Vectors Injected Systemically or into the CNS -- CH36;15 Cancer Vaccines -- CH36;16 Genetically Modified T Cells for Human Gene Therapy -- CH36;17 Lentiviral Vector Delivery of RNAi for the Treatment of HIV45;1 Infection -- CH36;18 Vector Targeting -- THE MANUFACTURE OF GENE THERAPY PRODUCTS -- CH36;19 The Manufacture of Genetic Viral Vector Products -- CH36;20 The Manufacture of Adeno45;Associated Viral Vectors -- CH36;21 Lentivirus Vector Manufacturing -- SAFETY AND REGULATORY CONSIDERATIONS -- CH36;22 Assays for the Release of Viral Vector Gene Therapy Products for Human Clinical Trials -- CH36;23 Safety of Retroviral Vectors58; Regulatory and Technical Considerations -- CH36;24 Assays for the Quality Control of Lentiviral Vectors -- CH36;25 Assays for Nonviral Vectors -- CH36;26 Assays for the Release of Cellular Gene Therapy Products -- CH36;27 Toxicology for Gene Therapy Products58; Concepts and Challenges -- CH36;28 Regulatory Aspects of Gene Therapy Medicinal Products in the European Union -- FINANCE AND REIMBURSMENT -- CH36;29 Venture Capital and Biotechnology Startups -- CH36;30 The Role of Investment Banking in the Growth of Biotechnology Companies -- CH36;31 Managing Reimbursement for Gene Therapy Products -- IDX36;INDEX -- Last Page. |
| 520 ## - ABSTRACT |
|---|
| Abstract |
A collection of reviews that highlight the most important issues in the development, manufacture, and commercialization of novel genetic medicines While the field of gene therapy is still a relatively young discipline, it is rapidly evolving and is characterized by impressive scientific and medical innovation. In Concepts in Genetic Medicine, readers are offered a collection of uniformly organized and succinct reviews in the field of therapeutic genetic medicine presented by a carefully selected group of top experts. Each chapter focuses on a single, current topic and explains issues in the development of genetic treatments, critical challenges and strategies for implementing them, and future directions in research and translational applications. Beginning with an introduction to the genetic basis of disease and a discussion of specific diseases, their etiology, and promising therapeutic treatments, the book goes on to cover vector design, genetic payloads and disease targets, vaccine vector systems, manufacture, assays, cell systems and target issues, preclinical testing, regulatory considerations, clinical evaluation, safety concerns, and commercialization. Complete with uniformly designed illustrations and a supplementary Web site with a PowerPoint presentation for educators, this is a practical guide for physicians, scientists, allied health workers, and patient advocacy professionals attempting to develop genetic medicines for translation into the clinic. |
| 546 ## - LANGUAGE NOTE |
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| Language note |
English. |
| 590 ## - LOCAL NOTE (RLIN) |
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| Local note |
WorldCat record variable field(s) change: 650 |
| 650 #0 - SUBJECT HEADINGS |
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| Subject term |
Medical genetics. |
| 650 #0 - SUBJECT HEADINGS |
|---|
| Subject term |
Gene therapy. |
| 650 #0 - SUBJECT HEADINGS |
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| Subject term |
Genetic vectors. |
| 650 12 - SUBJECT HEADINGS |
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| Subject term |
Genetic Therapy |
| General subdivision |
methods |
| 650 22 - SUBJECT HEADINGS |
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| Subject term |
Gene Transfer Techniques |
| 650 22 - SUBJECT HEADINGS |
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| Subject term |
Genetic Vectors |
| 650 22 - SUBJECT HEADINGS |
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| Subject term |
Viruses |
| General subdivision |
genetics |
| 650 #2 - SUBJECT HEADINGS |
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| Subject term |
Genetics, Medical |
| 650 #2 - SUBJECT HEADINGS |
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| Subject term |
Genetic Therapy |
| 700 1# - ADDED PERSONAL NAME |
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| Added personal author |
Dropulic, Boro. |
| 700 1# - ADDED PERSONAL NAME |
|---|
| Added personal author |
Carter, Barrie. |
| 856 40 - ONLINE RESOURCE |
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| Uniform Resource Identifier |
<a href="https://search.ebscohost.com/login.aspx?custid=ns123844&authtype=ip,shib&direct=true&scope=site&db=nlebk&db=nlabk&AN=225566">https://search.ebscohost.com/login.aspx?custid=ns123844&authtype=ip,shib&direct=true&scope=site&db=nlebk&db=nlabk&AN=225566</a> |
| Link text |
Kingston Hospital NHS Foundation Trust OpenAthens account holders click here for access |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Suppress in OPAC |
Do not Suppress in OPAC |
| 347 ## - DIGITAL FILE CHARACTERISTICS |
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| File type |
data file |
| 588 0# - SOURCE OF DESCRIPTION NOTE |
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| Source of description note |
Print version record. |
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123Library |
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123L |
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15039 |
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Askews and Holts Library Services |
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ASKH |
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AH3912705 |
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ebrary |
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EBRY |
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ebr10296153 |
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EBSCOhost |
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EBSC |
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225566 |
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ProQuest MyiLibrary Digital eBook Collection |
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IDEB |
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128442 |
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YBP Library Services |
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YANK |
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2808639 |
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YBP Library Services |
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YANK |
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2939933 |
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92 |
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N$T |